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Abstract Venetoclax requires a 75% dose reduction when coadministered with voriconazole. In a 10-year historical cohort of treatment with venetoclax, we did not observe a worse hematologic outcome in patients… Click to show full abstract
Abstract Venetoclax requires a 75% dose reduction when coadministered with voriconazole. In a 10-year historical cohort of treatment with venetoclax, we did not observe a worse hematologic outcome in patients who received voriconazole prophylaxis versus those who did not. Subtherapeutic voriconazole levels and a triazole exposure history may contribute to breakthrough invasive fungal infection.
Keywords:
invasive fungal;
infection coadministration;
breakthrough invasive;
coadministration venetoclax;
fungal infection
Journal Title: Open Forum Infectious Diseases
Year Published: 2023
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Journal Title: Open Forum Infectious Diseases
Year Published: 2023
Link to full text (if available)
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recommendations!