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Anaplasmosis-Induced Hemophagocytic Lymphohistiocytosis: A Case Report and Review of the Literature

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Abstract Cases of anaplasmosis have increased steadily and are appearing in states where it is less common. While symptoms are usually mild, in rare cases it can cause hemophagocytic lymphohistiocytosis.… Click to show full abstract

Abstract Cases of anaplasmosis have increased steadily and are appearing in states where it is less common. While symptoms are usually mild, in rare cases it can cause hemophagocytic lymphohistiocytosis. Here, we present a case of polymerase chain reaction–confirmed Anaplasma phagocytophilum with morulae on peripheral blood smear associated with biopsy-proven hemophagocytic lymphohistiocytosis.

Keywords: lymphohistiocytosis; anaplasmosis induced; hemophagocytic lymphohistiocytosis; lymphohistiocytosis case; induced hemophagocytic

Journal Title: Open Forum Infectious Diseases
Year Published: 2023

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