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First-dose antimicrobial infusion reactions in patients enrolled in outpatient parenteral antimicrobial therapy (OPAT) services

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Abstract After receiving a monitored first-dose antimicrobial infusion at an infusion center, 6 of 93 (6%) patients enrolled in outpatient parenteral antimicrobial therapy services experienced an immediate reaction, none of… Click to show full abstract

Abstract After receiving a monitored first-dose antimicrobial infusion at an infusion center, 6 of 93 (6%) patients enrolled in outpatient parenteral antimicrobial therapy services experienced an immediate reaction, none of which were consistent with immunoglobulin E-mediated reactions. These findings suggest it would be reasonable to forgo monitoring for most patients receiving first-dose intravenous antimicrobials outpatient.

Keywords: patients enrolled; dose antimicrobial; antimicrobial infusion; first dose; enrolled outpatient; infusion

Journal Title: Open Forum Infectious Diseases
Year Published: 2023

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