LAUSR

Abstract Background Measuring antimicrobial usage is a hallmark of antimicrobial stewardship programs. Service –level antimicrobial consumption data is easily obtained but offers limited value to individual clinicians. More specific data via spot audit is resource intensive to collect and may not reflect true practice. Additionally, though clinicians may prescribe antimicrobials with differing frequency, there may also be variability in the choice and spectrum of antimicrobials prescribed. We developed an individualized multidimensional tool using available prescribing and dispensing data to enhance peer comparison and feedback on antimicrobial prescribing. Methods Development was conducted in a 442-bed academic acute care hospital in the division of General Internal Medicine (GIM), in Toronto, Canada. Physician-specific antibiotic consumption data (DDD/100 patient days and DOT/100 patient days) was obtained between February 15th and August 24th, 2016. Summative spectrum of activity was calculated using a metric assigning a value from 0 to 60 to each antimicrobial and obtaining a weighted average of total antimicrobial prescribing by clinician (spectrum scorephysician, modified from Madaras-Kelly et al 2014). Results Mean antimicrobial consumption was 39.1 ± 13.5 DDD/100 patient-days and 38.5 ± 8.4 DOT/100 patient-days. There was significant variability between the lowest and highest prescribers in both the DDD and DOT (3.3-fold difference DDD/100 patient days, 2.2-fold difference DOT/100 patient days). Mean spectrum score was 23.7 ± 1.8 (approximating Second generation cephalosporins). Variability was also pronounced in this group with the minimum prescriber being 19.5 (equivalent to cefazolin) and maximum being 26.7 (more broad than ceftriaxone). Feedback of this data were given individually to clinicians with other prescribers de-identified. Physicians found the data to be easy to understand and acceptable for further use. Conclusion Individualized feedback of summative antimicrobial consumption and spectrum provides insight to clinicians. This data can be considered to promote peer comparison and reflection of antimicrobial prescribing. This tool may also be helpful for benchmarking antibiotic usage within and between institutions. Disclosures All authors: No reported disclosures.