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Abstract Cryptococcus gattii infections, especially including those with severe clinical manifestations, may be related to underlying host immunologic factors. We present 2 cases with autoantibodies to granulocyte-macrophage colony-stimulating factor (GM-CSF),… Click to show full abstract
Abstract Cryptococcus gattii infections, especially including those with severe clinical manifestations, may be related to underlying host immunologic factors. We present 2 cases with autoantibodies to granulocyte-macrophage colony-stimulating factor (GM-CSF), a key cytokine in macrophage function. Immunologic evaluation for anti-GM-CSF antibodies may be important to inform management and counseling.
Keywords:
gattii infections;
macrophage colony;
cryptococcus gattii;
autoantibodies granulocyte;
macrophage;
granulocyte macrophage
Journal Title: Open Forum Infectious Diseases
Year Published: 2017
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Journal Title: Open Forum Infectious Diseases
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!