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Invasive Genitourinary Aspergillosis in a Patient with Chronic Lymphocytic Leukemia Treated with Venetoclax: Case Report and Review of the Literature

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Novel targeted pharmacotherapies have ushered in a new era in the management of chronic lymphocytic leukemia (CLL). Postmarketing surveillance indicates that some of these agents are associated with unexpected increases… Click to show full abstract

Novel targeted pharmacotherapies have ushered in a new era in the management of chronic lymphocytic leukemia (CLL). Postmarketing surveillance indicates that some of these agents are associated with unexpected increases in opportunistic infections. In this report, we present a case of primary genitourinary invasive aspergillosis in a patient with CLL treated with venetoclax. We briefly review both genitourinary aspergillosis and infection risks associated with venetoclax treatment for CLL.

Keywords: lymphocytic leukemia; aspergillosis; aspergillosis patient; genitourinary aspergillosis; chronic lymphocytic; treated venetoclax

Journal Title: Open Forum Infectious Diseases
Year Published: 2019

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