LAUSR

Perineural injection therapy (PIT) is one of the latest advancements in regenerative medicine. It targets cutaneous nerves as a potential pain generator. First described by Dr. Paul Pybus and Dr. Roger WyburnMason, PIT targets neurogenic inflammation in subcutaneous nerves that potentially generates pain [1,2]. PIT was further refined by Dr. John Lyftgoft using dextrose injection, which provided substantial pain control in a series of 300 Achilles tendinopathy [3]. However, this treatment approach remains largely unknown; thus we sought to document the effect of PIT in the management of complex regional pain syndrome (CRPS) and its outcome on pain and functional restoration.