LAUSR

Immonen J, Jääskeläinen E, Korpela H, Miettunen J. Age at onset and the outcomes of schizophrenia: systematic review and meta-analysis. Early Interv Psychiatry, in press. Jääskeläinen E, Juola P, Hirvonen N, McGrath JJ, Saha S, Isohanni M, Veijola J, Miettunen J. A systematic review and meta-analysis of recovery in schizophrenia. Schizophr Bull 2013; 39:1296-1306. Käkelä J, Panula J, Oinas E, Hirvonen N, Jääskeläinen E, Miettunen J. Family history of psychosis and social, occupational and global outcome in schizophrenia: a meta-analysis. Acta Psychiatr Scand 2014; 130:269-78. Penttilä M, Jääskeläinen E, Hirvonen N, Isohanni M, Miettunen J. Duration of untreated psychosis as predictor of long-term outcome in schizophrenia. A systematic review and metaanalysis. Br J Psychiatry 2014; 205:88-94. 33 studies investigated associations between DUP and outcomes. DUP associated with poor general symptomatic outcome, more severe positive and negative symptoms, lower likelihood of remission, poor social functioning, and poor global outcome (correlations 0.13–0.18) (Penttilä et al. 2014). 14 studies investigated associations between family history of psychosis and outcomes. Family history of psychosis was associated with poor occupational (r=0.17) and global (r=0.13) outcome (Käkelä et al. 2014). 81 studies investigated associations between onset age and outcomes. Earlier onset age associated with more hospitalizations, negative symptoms, relapses, worse social/occupational functioning, and poorer global outcome (correlations 0.11–0.17) (Immonen et al. In press).