LAUSR

Learning Objectives: Shock is one of the most common deadly issue in critical care unit (ICU),valve hemodynamic change was very common in shock patients. The aim of this study was to investigate the prognostic value of mitral regurgitation(MR) in shock patients in intensive care unit (ICU). Methods: This prospective study of the shock patients in CCUS was conducted in 181 adult patients between April 2016 to June 2017 in Western China Hospital. CCUS was performed within the initial 6 hours after patients were enrolled. The shock patients’ demographics, clinical characteristics, the ultrasonic pattern of hemodynamics and outcome had been described. A bivariate logistic regression model was established to identify the correlation between the ultrasonic variables and the 28-day mortality on shock patient. Results: A total of 181 patients with shock were enrolled, and 44.8%(81/181) patient died within 28 days after ICU admission. 113 males and 68 females, average age was 58.15 ± 18, average APACHE II Score was 23.73 ± 8.7. The multivariate analysis demonstrated that MR was the independent risk factors for 28-day mortality, as well as early diastolic transmitral velocity to early mitral annulus diastolic velocity ratio (E/e`-MV), Lung Ultrasound Score(LUSS) and Increased transTricispid Flow(ITF) (P=0029, 0.026, 0.011 and 0.048, respectively). In the Kaplan-Meier survival analysis, there were significant differences in survival among patients in the MR and non-MR groups (=4.448, P=0.035). Conclusions: MR was associated with 28-day mortality. Shock patients without MR had a higher survival rate.