LAUSR

Objective: To evaluate influence of patient's compliance with chronic coronary artery disease (CAD) on clinical course of the disease. Design and method: 72 patients (pts) with CAD, who had undergone treatment in cardiology department from may to august 2016 were included in our study (50 males (69,4%), 22 females (30,56%); average age 63,6 ± 9,59 years), these pts were questioned with Morisky Adherence Test. Results: 34 pts were compliant (47,2%), 20 were partially uncompliant (27,8%) and 18 were uncompliant (25%). There was no difference in uncompliance between males and females (54,5%). There were several significant reasons of uncompliance: underestimation of disease severity by patient, medication cancellation by patient due to positive dynamics and forgetfulness. Underestimation of disease severity by patient and medication cancellation by patient due to positive dynamics were more common among males, 86,7% and 75% among pts who pointed these reasons respectively. Only 37 pts (51,4%) received proper antiplatelet and hypolipidemic treatment. Average level of total cholesterol (TC) was significantly lower (p < 0,0001) in compliant pts than in partially uncompliant and uncompliantpts (4,4 ± 0,86 mmol/l vs 6,1 ± 1,74 mmol/l). Average level of low-density lipoproteins (LDL) – 2,78 ± 0,74 mmol/l vs 3,54 ± 1,16 mmol/l respectively (p < 0,002); average level of triglycerides (TG) – 1,56 ± 0,7 mmol/l vs 2,01 ± 1,42 mmol/l respectively (p < 0,01). In the group of with previously confirmed myocardial infarction (MI) 15 pts (53,6%) were compliant. In the group of pts who had previously undergone PCI or CABG 21 patient (58,3%) was compliant. Conclusions: Significant part of pts with CAD administered to cardiology department were not compliant (52,8%) and didn’t receive proper antiplatelet and hypolipidemic treatment (51,4%). MI didn’t increase compliance, nor PCI or CABG did. Main reasons of uncompliance were underestimation of disease severity by patient and medication cancellation by patient due to positive dynamics.