LAUSR

Objectives: To explore Takayasu's arteritis (TA) is an independent risk factor for the increase of the brachial-ankle pulse wave velocity (baPWV). Methods: We respectively analyzed the baPWV in consecutive 193 inpatients diagnosed with TA from January 2013 to January 2016 in Fuwai Hospital. 150 patients with primary hypertension and 150 healthy people were enrolled for comparing as controls after adjusting sex, age and systolic blood pressure. We compared baPWV of TA patients with controls. In addition, the independent risk factors of elevated baPWV were analyzed by unconditional multifactor logistic regression. Results: For 43 (46.2%) TA patients without hypertension, the mean baPWV was 1241.6 ± 231.4 cm/s respectively, which was higher than normal controls (P < 0.05). And for 50 (53.7%) TA patients accompanied with hypertension, the mean baPWV was 1366.8 ± 256.1 cm/s, there was no significant difference between the TA patients accompanied with hypertension and primary hypertension patients. The unconditional multivariate logistic analysis showed TA (OR = 2.117, 95%CI = 1.102–4.065, P < 0.05) was independent risk factor for higher baPWV. Conclusion: The baPWV in TA patients without hypertension was higher than healthy controls and TA was the independent factor for the high baPWV, which suggest TA was determinant associated with arterial stiffness.