Objective: To assess the incidence and prognostic impact of cardio-renal syndrome (CRS) in a population of patients admitted for an acute coronary syndrome (ACS), Design and method: This was a… Click to show full abstract
Objective: To assess the incidence and prognostic impact of cardio-renal syndrome (CRS) in a population of patients admitted for an acute coronary syndrome (ACS), Design and method: This was a retrospective cohort study of 952 patients with ACS. An information sheet was established for data collection. Cumulative survival rates were obtained by the Kaplan Meier method, survival curves were compared by the Log-Rank test, the ROC curve was used to define the cut-offs of the markers of renal function to predict mortality Results: The incidence of cardio-renal syndrome was 54.8%, and it was more frequent in women, elderly subjects, hypertensives and diabetics. The cut-offs of creatinine and uremia to predict mortality were 15.7 mg/l and 0.65 g/l respectively. Cumulative survival rates were lower in the group of patients with CRS-1. Conclusions: The cardio-renal syndrome is a frequent complication in patients admitted for ACS. Creatinine levels, as well as uremia, are easy to measure, accessible, and very inexpensive parameters that have very satisfactory predictive capacities in the context of CRS-1
               
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