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54/438 (12.3%) patients with PARDS from 5/10 (50.0%) centers were ventilated with NIV on day 1 of PARDS and included in this analysis. The median age, Pediatric Index of Mortality… Click to show full abstract
54/438 (12.3%) patients with PARDS from 5/10 (50.0%) centers were ventilated with NIV on day 1 of PARDS and included in this analysis. The median age, Pediatric Index of Mortality 2 score and oxygen saturation/ fraction of inspired oxygen ratio was 50.3 (12.6, 110.6) months, 16.0 (9.5, 17.6) % and 156.7 (119.7, 192.5) respectively. NIV was mainly used for increased work of breathing [27/54 (50.0%)] and hypoxia [22/54 (40.7%)]. 31/54 (57.4%) were supported on bilevel positive airway pressure ventilation. NIV failure occurred in 47/54 (87.0%) and was associated with increased median length of PICU [13.0 (8.0, 25.0) vs. 5.0 (3.0, 6.0) days; p < 0.001] and hospital stay [25.0 (17.0, 38.0) vs.11.0 (8.0, 21.0) days; p = 0.018]. Overall mortality rate was 17/54 (31.5%). There was limitation of care/ do-not-resuscitate orders for 10/54 (18.5%) patients, although only 7/10 (70.0%) of these died.
Journal Title: Pediatric Critical Care Medicine
Year Published: 2018
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