LAUSR

126 children were admitted to PICU with ALF with median age of 2.1 years (0–9.45 years). Most patients had ALF due to indeterminate etiology (38.8%).At admission, 38.1% children had any stage AKI predominantly severe AKI (89.3%). The incidence of AKI increased by day 4 (53.5%), and decreased by day 7(47.0%).Most patients progressed to severe AKI in the first week (95.5%). Children with AKI (Vs no AKI) required ventilation more often (60.6% Vs 39.32%, P=0.015) and increased duration of ventilation [8(0–105) vs 3(0–18)]. Children with severe AKI had a longer PICU stay[7.9(1–30) vs 13.37 (1–183) days].Mortality rate was higher in the AKI group(16.3% versus 8.1%) and it correlated with increasing stage of AKI as well (20/62 vs 0/3). It also increased requirement for liver transplant (6/54 Vs 33/67). However, in most patients AKI resolved. No patient required RRT at discharge.