LAUSR

Background Recently, complex living donors with marginal factors including hypertension, dyslipidemia, glucose intolerance, and obesity are increasing. Postoperative kidney functions of living donors for kidney transplantation are of our great concern. We investigated the pathological findings of control biopsy and postoperative kidney functions evaluated with estimated glomerular filtration rates (eGFR) of the complex living donors. Methods Between January 2008 and December 2016, 805 living donors for kidney transplantation were included in this study. Marginal criteria for complex living donors include hypertension, dislipidemia, glucose intolerance, and obesity. Living donors were stratified into 2 groups (Healthy living donor and Complex living donor). 215, and 590 living donors were classified into Healthy living donor and Complex living donor, respectively. Pathological findings of control biopsy and postoperative eGFRs were compared. Control biopsies were obtained one hour after the reperfusion of the transplanted kidney and examined by transplant pathologists. Results In pathological findings of control biopsies, obsolescent glomerulus or arteriolosclerosis were identified significantly more in the Complex living donor than Healthy living donor (P<0.001). In postoperative eGFRs, no significant differences were identified in each point of observation periods. Conclusion Postoperative kidney function of complex living donors can be maintained in spite of the pathological findings of control biopsies. Figure. No caption available.