LAUSR

Introduction: There are recent data stating that women experience not only disadvantages as liver transplant recipients, however they seem to be chosen more frequently as living donors as well. Since we recently reviewed the donors at our centre in Germany where we mainly perform left lateral living donor recection for pediatric recipients, and found that we indeed have a majority of mothers donating for their infant recipients, we initiated the idea to compare our data with a centre in Saudi Arabia. As women generally have had fewer rights in this country one might expect a similar distribution amongst living donors. Since politics are emerging to change this might be proven wrong. We therefore compared the last 50 living donors for pediatric recipients receiving left lateral lobe grafts in both centers. Materials and Methods: In the German center we needed donors of the last 5 years in order to achieve a number of 53 donors, in the Saudi Arabian centre these donors were accumulated within only one year. In the German center we selected 23 men and and 30 females as donors. All of them were parents. In the Saudi Arabian centre there were only 13 female donors, and therefore 37 male donors. Interestingly there were only 3 mothers amongst the female donors, 3 aunts, two sisters, one cousin and 4 unrelated donors. Of the 37 male there were 16 fathers, 4 brothers, 5 uncles, one cousin and 11 unrelated donors. Results: There was no difference in GBWR, cold and warm ischemic or liver quality between centers and gender. However the average donor age in the Saudi Arabian center was significantly lower 21.6 compared to 28.3 in the German centre. However many donors in the German center were from families with migrational background (refugees, other EU countries). In the German center 6 male donors were evaluated as donors, but were rejected to due to comorbidities or drug consume. Conclusions: Since there are no anatomical or qualitative differences between male and female liver donors for the left lateral lobe, the difference amongst gender distribution must lie with the evaluating physicians or the willingness of potential donors to undergo this procedure. A main difference in Saudi Arabia is, that there is an option for someone to voluntarily donate an organ in an undirected unrelated setting out of generosity. These donors however were only 15 out of 50. The majority of donors therefore came from within the family. Here again less parents donated than in Germany and more siblings and second degree relatives. This can easily be explained by bigger and younger families in Saudi Arabia. However the willingness to donate has to be emphasized. We therefore conclude, that women and especially mothers must be considered as much more important within their role in possibly the mother to other children and the integrity of the family. Therefore they seem to be protected from additional burden by their relatives, other as it might be in western centers. P-4.46