A total of 11 patients remain active. The most common reasons for dismissal (N=25) were nonadherence or loss to follow-up (N=6), provider specific management or resistance to the protocol (N=5),… Click to show full abstract
A total of 11 patients remain active. The most common reasons for dismissal (N=25) were nonadherence or loss to follow-up (N=6), provider specific management or resistance to the protocol (N=5), and adverse events (N=4) including hypercalcemia/ hypercalciuria (N=3) and calciphylaxis (N=1) that was attributed to inadequate dialysis. Goal POx was achieved in 80% of those with an initially elevated value including all KTx recipients prior to transplant. KTx recipients (12 living donor) had a median 0.7 (0.4-1.8) years post-transplant follow up. Only one DGF event occurred in a deceased donor recipient who also manifests numerous calcium oxalate crystals on a 1 year protocol biopsy. Of the remaining KTx recipients, two had rare calcium oxalate deposition on protocol biopsies with one additional recipient developing new stones attributed to hypocitraturia since they had a normal POx and UOx. All grafts were functioning at last follow-up. Conclusion: This study demonstrated the feasibility of a nurse driven protocol to successfully lower POx and UOx in EH patients prior to KTx. While nonadherence was common, among the remainder POx and UOx achieved target and the protocol was well tolerated. Outcomes post-transplant are favorable especially in living donor recipients. P-11.193
               
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