LAUSR

To the Editor: It is with great interest that we recently read two articles— Estrup et al (1) and Sakusic et al (2)—concerning the impairment of cognitive functions after an ICU stay, which were published in a recent issue of Critical Care Medicine. Reports on cognitive functioning after illness, surgical procedure, or cardiopulmonary resuscitation have been widely presented in literature in recent years. This is a very important issue, as the researchers aim at identifying modifiable risk factors for cognitive impairment (CI), as well as the test types which would be most useful for cognitive functional testing. Sakusic et al (2) identified the potential risk factors for CI after an ICU stay, namely acute brain failure, severe hypotension, hypoxemia, hyperthermia, fluctuations in serum glucose levels, and treatment with vancomycin or quinolones. On the other hand, authors of earlier studies found that hyperglycemia requiring insulin therapy after surgical procedures is one of the CI risk factors We thank the author for bringing our attention to the typing error. This is to be corrected to “All included studies were reported between 2001 and 2017.” To conclude, we agree that there is a difference between a literature review and a systematic review. We conducted a systematic review and meta-analysis. We restricted our metaanalysis to the 10 articles with available data. We welcome a meta-analysis on the subject matter or an independent discussion of our results from Dr. Nadeem (1). Dr. Johnson-Akeju received support for article research from the National Institutes of Health. Dr. Fadayomi disclosed that they do not have any potential conflicts of interest.