LAUSR

Additional testing, including various laboratory diagnosTo the Editor:Motor neuron disease (MND) is marked by upper (UMN) or lower (LMN) motor neuron signs and [1] tics (eg, anti-GM1, anti-GD1b, anti-GQ1b antibodies, and symptoms, which in various combinations form the basis for MND classification. In this regard, amyotrophic lateral sclerosis (ALS) is the most common subtype. Although otherwise deemed an untreatable degenerative disease, there is now increasing evidence of more heterogeneous pathogenesis, signaling a link between MND and paraneoplastic syndromes.