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MicroRNA-98 can serve as a diagnostic marker for congenital heart disease-associated pulmonary artery hypertension

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Congenital heart disease (CHD) has become the leading the instructions of a qPCR kit (Thermo Fisher Scientific, mortal cause for an infant from congenital abnormalities. Shanghai, China). The relative expression… Click to show full abstract

Congenital heart disease (CHD) has become the leading the instructions of a qPCR kit (Thermo Fisher Scientific, mortal cause for an infant from congenital abnormalities. Shanghai, China). The relative expression of miR-98 was Pulmonary artery hypertension (PAH) is one of the complications of CHD. It has also been reported that upregulation of microRNA-98 (miR-98) could mediate the suppression of cardiac hypertrophy, which implies that miR-98 might play an important role in CHD. In this study, the clinical data from hospitalized patients were retrospectively analyzed to identify if there is any evidence of diagnosis of circulating miR-98 on CHD patients with PAH.

Keywords: heart disease; pulmonary artery; congenital heart; artery hypertension

Journal Title: Chinese Medical Journal
Year Published: 2020

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