LAUSR

To the Editor: Obscure gastrointestinal bleeding (OGIB) has been defined as bleeding of unknown origin that recurs or persists after gastroscopy, colonoscopy, enteroscopy, and radiographic testing, and occurs in approximately 5% of patients presenting with all gastrointestinal hemorrhages. The usual course of treatment includes transfusion support, hemostatic medication, endoscopic therapy, vascular embolization, and surgery. Patients with unstable hemodynamics, persistent bleeding, advanced age, increased complications, chronic renal failure, and severe anemia have a poorer prognosis. Platelet-rich plasma (PRP) contains growth factors and bioactive proteins that promote the healing of cutaneous and mucosal damage. Here, we report a case of incurable OGIB treated with nasointestinal tube feeding of PRP in a renal transplant patient with chronic graft failure.