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Real-life effectiveness and safety of secukinumab in axial spondyloarthritis: a single-center study

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Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended as a first-line drug for axSpA patients. Failed to NSAIDs therapy, tumor necrosis factor (TNF)-a inhibitor (TNFi) was suggested in the treatment strategy of… Click to show full abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended as a first-line drug for axSpA patients. Failed to NSAIDs therapy, tumor necrosis factor (TNF)-a inhibitor (TNFi) was suggested in the treatment strategy of axSpA. But 30% of axSpA patients still do not respond or respond inadequately to the TNFi therapy. Moreover, TNF-a antagonists are believed to have a weak effect on preventing osteophyte formation and spinal structure damage in axSpA.

Keywords: real life; axial spondyloarthritis; life effectiveness; safety secukinumab; secukinumab axial; effectiveness safety

Journal Title: Chinese Medical Journal
Year Published: 2022

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