LAUSR

To the Editor: The incidence of intraocular metastases is approximately 8% to 10%, of which choroidal metastasis (CM) is the most painful metastatic lesion. CM is a growing problem in the context of an aging population and improved survival among stage IV cancer patients. Lung cancer is the second most common primary malignancy associated with CM. Clinical symptoms vary greatly depending on the location of the lesion or the degree of invasion. Acute clinical symptoms will significantly impair quality of life among surviving patients. The main therapeutic modalities include systemic and local treatments, while observation is also a treatment option. Currently, the feasibility and effectiveness of various treatment options are controversial around the world. Given the rarity of this condition, it is almost impossible to conduct large-scale clinical trials to validate optimal treatment modalities, rather, clues and insights may derive from a series of small sample reports. Herein, we reviewed the related literature from 2009 to 2019, from which relevant information was extracted to elucidate the epidemiological and clinical characteristics of CM and to provide suggestions for the treatment of this condition.