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Pemphigus Foliaceus Demonstrating Pathergy After Mohs Micrographic Surgery.

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Pathergy is the appearance of disease-specific lesions of inflammatory dermatoses at the sites of trauma. Diseases commonly reported to demonstrate pathergy, analogous to theKoebner phenomenon, are psoriasis, lichen planus, vitiligo,… Click to show full abstract

Pathergy is the appearance of disease-specific lesions of inflammatory dermatoses at the sites of trauma. Diseases commonly reported to demonstrate pathergy, analogous to theKoebner phenomenon, are psoriasis, lichen planus, vitiligo, pyoderma gangrenosum, and Behcet disease. Bullous diseases have rarely been reported to have pathergic potential. When surgery is considered in patients known to have diseases with pathergic potential, immunomodulatory coverage is often considered; however, Mohs surgeons may not be aware of the pathergic potential of bullous diseases after Mohs micrographic surgery (MMS) that maymimicmalignant recurrence. In this article, we report a case of pemphigus foliaceus (PF) demonstrating pathergy in the donor and recipient site masquerading as dermatitis and clinical recurrence after MMSwith a subsequent full-thickness skin graft (FTSG).

Keywords: surgery; foliaceus demonstrating; mohs micrographic; pemphigus foliaceus; demonstrating pathergy; micrographic surgery

Journal Title: Dermatologic Surgery
Year Published: 2018

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