Antibiotic prophylaxis is used to prevent surgical site infections (SSIs) that can cause significant morbidity from pain, delayed wound healing, and impaired cosmesis. High-risk patients including those with prosthetic heart… Click to show full abstract
Antibiotic prophylaxis is used to prevent surgical site infections (SSIs) that can cause significant morbidity from pain, delayed wound healing, and impaired cosmesis. High-risk patients including those with prosthetic heart valves and implantable devices are often given antibiotic prophylaxis. Evidence with respect to oral and intraincisional antibiotic prophylaxis is nebulous, and previous studies regarding this have shown inconsistent results. The impetus of the current novel metaanalysis was to assess whether oral and intraincisional antibiotics provided significant improvement of SSI.
               
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