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associated with NS. The most common benign neoplasms associated with NS are trichoblastoma and syringocystadenoma papilliferum. Basal cell carcinoma is the most common malignant neoplasm occurring in sebaceous naevi (5%–7%).… Click to show full abstract
associated with NS. The most common benign neoplasms associated with NS are trichoblastoma and syringocystadenoma papilliferum. Basal cell carcinoma is the most common malignant neoplasm occurring in sebaceous naevi (5%–7%). Less common malignant tumors include squamous cell carcinoma, apocrine and adnexal carcinoma, and eccrine poroma. Some authors suggest that NS should be considered premalignant lesions since malignant degeneration, most commonly basal cell carcinoma and squamous cell carcinoma, occurs with a lifetime risk of between 5% and 22%. Neoplastic transformation of NS occurs rarely in children.
Journal Title: Dermatologic Surgery
Year Published: 2019
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