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Sensitivity Analyses for Means or Proportions with Missing Outcome Data.

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We describe an approach to sensitivity analysis introduced by Robins and colleagues, for the setting where the outcome is missing for some observations. This flexible approach focuses on the relationship… Click to show full abstract

We describe an approach to sensitivity analysis introduced by Robins and colleagues, for the setting where the outcome is missing for some observations. This flexible approach focuses on the relationship between the outcomes and missingness, where data can be missing completely at random, missing at random given observed data, or missing not at random. We provide examples from HIV that include the sensitivity of the estimation of a mean and proportion under different missingness mechanisms. The approach illustrated provides a method for examining how the results of epidemiologic studies might shift as a function of bias due to missing data.

Keywords: sensitivity analyses; proportions missing; means proportions; sensitivity; analyses means; missing outcome

Journal Title: Epidemiology
Year Published: 2023

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