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Reply to: deep neuromuscular blockade reduces intra-operative blood loss.

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Third, the data about the surgeons’ satisfaction with the intra-operative surgical conditions and the postoperative pain score do not allow valid conclusions because of lack of a power calculation, lack… Click to show full abstract

Third, the data about the surgeons’ satisfaction with the intra-operative surgical conditions and the postoperative pain score do not allow valid conclusions because of lack of a power calculation, lack of information regarding accuracy and precision of the methods used for the assessments, lack of assurance that the surgeons had been blinded to the patient’s assignment, a mere single pain assessment at 30 min after transfer to the postanaesthesia care unit and lack of confidence intervals. Considering these limitations, the clinical relevance of a difference in mean surgeons’ satisfaction score of 0.6 and in median postoperative pain scale of 10 is highly questionable. Comparable surgical times and blood losses support the questionable clinical relevance of the statistically significant difference in surgeons’ satisfaction score.

Keywords: reply deep; blood; intra operative; neuromuscular blockade; deep neuromuscular; surgeons satisfaction

Journal Title: European Journal of Anaesthesiology
Year Published: 2020

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