ABSTRACT Rapid advancements in oncological treatments over the past few decades have led to a significant improvement in cancer outcomes. Chemotherapeutic agents play a pivotal role in cancer treatment, with… Click to show full abstract
ABSTRACT Rapid advancements in oncological treatments over the past few decades have led to a significant improvement in cancer outcomes. Chemotherapeutic agents play a pivotal role in cancer treatment, with almost one third of patients receiving them during their cancer treatment in the United Kingdom.1 The success of chemotherapeutic drugs has, however, resulted in an increasing incidence of cardiovascular side effects and complications. The most common cardiac manifestation is the development of cardiotoxicity, defined as the development of left ventricular systolic dysfunction following treatment. This article provides an up-to-date review of commonly used chemotherapeutic agents that cause cardiotoxicity, as well as discussing current treatment options and evidence gaps.
               
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