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WHAT IS THE THERAPEUTIC REFERENCE RANGE FOR LEVETIRACETAM?

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The Therapeutic Drug Monitoring guidelines of Arbeitsgemeinschaft fur Neuropsychopharmakologie und Pharmakopsychiatrie had proposed a therapeutic reference range of 10-40 mg/L for levetiracetam in 2011. In the first version of the… Click to show full abstract

The Therapeutic Drug Monitoring guidelines of Arbeitsgemeinschaft fur Neuropsychopharmakologie und Pharmakopsychiatrie had proposed a therapeutic reference range of 10-40 mg/L for levetiracetam in 2011. In the first version of the 2017 update, it was changed to 20-40 mg/L; however, 5 months later, in an erratum version, it was changed back to 10-40 mg/L. Here, the authors agree with the range to 10-40 mg/L, but discuss to what extent a wider interval may be proposed for certain patients.

Keywords: range levetiracetam; range; therapeutic reference; reference range

Journal Title: Therapeutic drug monitoring
Year Published: 2022

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