PURPOSE To describe and analyze clinical characteristics of multifocal choroiditis (MFC) with linear streaks (LSs). METHODS Eight cases of MFC with LSs were retrospectively studied. Multimodal imaging was performed. Demographic… Click to show full abstract
PURPOSE To describe and analyze clinical characteristics of multifocal choroiditis (MFC) with linear streaks (LSs). METHODS Eight cases of MFC with LSs were retrospectively studied. Multimodal imaging was performed. Demographic data and spherical equivalent were collected. Axial length was measured. RESULTS All cases are young myopic females with a mean age of 17.13±3.64 years (range, 13-23 years), presenting with vision loss and distortion. Nine eyes with LSs were high myopia of -8.97±2.69D (range, -6.00-12.5D; growing by 1.88±0.61D annually since wearing glasses), with mean axial length of 26.36±1.71mm. Vitreous cells were noted in 7 eyes. LSs were located in equator (8 eyes), around optic disc (3 eyes) and at the edge of posterior pole (1 eye). Angio-OCT showed choroidal neovascularization (CNV) in 8 eyes, especially 2-3 CNVs in 3 eyes. The location of CNV were in subfovea (3 eyes), parafovea (6 eyes) and perifovea (2 eyes). SS-OCT showed punched-out disruption of RPE-Bruch's-membrane-choriocapillaris-complex at the LSs' sites. LSs showed fluorescence staining on late-FA, but hypofluorescence throughout all phases on ICGA. CONCLUSION MFC with LSs mostly occurs in young females with high myopia, especially occurring in eyes with rapid progression of myopia. LSs are mainly located in mid-periphery near equator, being prone to concur with CNV. Based on our findings, we propose a new term called 'Streaky Multifocal Choroiditis (SMFC)' as a subtype of MFC.
               
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