LAUSR

PURPOSE The sclera is reportedly thicker in eyes with central serous chorioretinopathy (CSC) than in healthy control eyes. We compared the scleral thicknesses of the affected and unaffected fellow eyes of patients with unilateral CSC. METHODS We retrospectively examined the findings of 115 patients with unilateral CSC. Comparisons of the spherical equivalent (SE), axial length, anterior chamber depth (ACD), subfoveal choroidal thickness (SCT), scleral thickness, and presence of peripheral ciliochoroidal effusion (CE) of the affected and fellow eyes were made. Using anterior segment optical coherence tomography, scleral thickness was measured vertically, 6 mm posterior to the scleral spur in the superior, temporal, inferior, and nasal directions. RESULTS No significant differences in scleral thickness in all four directions, SE, axial length, ACD, and frequency of CE were found between the affected and unaffected fellow eyes. The only significant difference between the affected and fellow eyes was observed in the SCT (398.8 µm vs. 346.6 µm, P < 0.001). CONCLUSION A thickened choroid seems to have a direct effect on CSC development. In contrast, the affected and fellow eyes showed no significant difference in scleral thickness, indicating that scleral thickening may be a predisposing factor for the development of CSC.