LAUSR

Purpose: To study the effect of myopia on the pattern change in higher-order aberrations after small incision lenticule extraction. Methods: Sixty eyes of 60 patients were included: low myopia (⩽−3.00 D), moderate myopia (−3.00 D to −6.00 D), and high myopia (≥−6.00 D). Total higher-order aberrations (tHOA), vertical coma ( ), horizontal coma ( ), and spherical aberration ( ) were measured preoperatively and at postoperative 3 months. Results: At the end of 3 months, tHOA changed significantly compared with the preoperative values (P < 0.05), except for and in the low myopia group. The change in , , and in the moderate group (−0.299, −0.175, and 0.108 &mgr;m) was 2.020, 4.861, and 4.696 times higher than the low group (−0.148, −0.036, 0.023 &mgr;m) (P = 0.002, 0.001, 0.001), respectively. The value in the high group (−0.331, −0.192, 0.154 &mgr;m) was 1.107, 1.097 (P = 0.478, 0.665), and 1.426 times (P = 0.047) higher than the moderate group. The degree of myopia was positively correlated with &Dgr; (r = 0.447; P < 0.001) and &Dgr; (r = 0.496; P < 0.001), and negatively correlated with &Dgr;tHOA (r = −0.363, P = 0.004) and &Dgr; (r = −0.599; P < 0.001). Conclusions: The study showed a different pattern of change in ocular aberrations after small incision lenticule extraction in patients with varying degrees of myopia. In patients with low myopia, there was no increase in or . In high myopia, however, increased with the degree of myopia, whereas the rising rate of coma was slowing.