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Is Autophagy Dysfunction a Key to Exfoliation Glaucoma?

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In this short report we review previous work toward the identification of the protein and cellular sources of exfoliation glaucoma and described our recent finding on dysfunction of autophagy in… Click to show full abstract

In this short report we review previous work toward the identification of the protein and cellular sources of exfoliation glaucoma and described our recent finding on dysfunction of autophagy in Tenon capsule fibroblasts obtained from exfoliation syndrome glaucoma patients at the time of surgery and discuss the potential implications of these findings for understanding the cellular sources of the disease.

Keywords: autophagy dysfunction; glaucoma autophagy; exfoliation glaucoma; glaucoma; exfoliation

Journal Title: Journal of glaucoma
Year Published: 2018

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