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Long-term Outcome of Ahmed Glaucoma Valve Implantation in Eyes with Intractably Raised Intraocular Pressure Following Pars Plana Vitrectomy.

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PRECIS Ahmed glaucoma valve implantation led to a significant reduction in intraocular pressure and in anti-glaucoma medications in vitrectomized eyes in previously non-glaucomatous eyes. The most common indication for vitrectomy… Click to show full abstract

PRECIS Ahmed glaucoma valve implantation led to a significant reduction in intraocular pressure and in anti-glaucoma medications in vitrectomized eyes in previously non-glaucomatous eyes. The most common indication for vitrectomy was ocular trauma related complications. PURPOSE To report the long-term outcomes of Ahmed Glaucoma Valve (AGV) implantation in patients of uncontrolled intraocular pressure (IOP) after pars plana vitrectomy (PPV). METHOD Medical records of patients (age ≥18▒y) who underwent AGV implantation between Jan-2006 to Dec-2017 for uncontrolled IOP following PPV with ≥2 years follow-up were reviewed. The underlying aetiology for PPV, IOP, best-corrected visual acuity (BCVA) and number of anti-glaucoma medications (AGM) were recorded at baseline. The main outcomes measures were IOP, number of AGM, BCVA and postoperative complications. Postoperative complications were classified as early (≤3▒mo)/intermediate (>3▒mo to ≤1▒y)/ late (>1▒y). RESULTS Seventy-eight eyes of 78 patients with a mean age of 38.06±17.83 years were included. The mean follow-up was 70.46±36.96 (range 24-180) months. The main underlying etiology for PPV was trauma (38.4%) followed by rhegmatogenous retinal detachment (28.2%). The mean pre-operative IOP was 29.33±9.84▒mmHg with an average of 4.07±1.2 AGM. The mean IOP and number of AGM was significantly reduced in all follow-up visits (P<0.0001) following AGV implantation. The cumulative probability of success was 92.3%, 80.7% and 74% at 2, 5 and 10 years respectively. Thirty-one complications were observed in 25 (32%) eyes and re-operation (23 procedures) was performed in 22 (28.2%) eyes. CONCLUSIONS AGV implantation had good outcome in patients with intractably elevated IOP following PPV. Trauma-related pathologies were a major contributor to the indications for PPV and had more chances of failure following AGV implantation.

Keywords: iop; glaucoma valve; agv implantation; implantation; ahmed glaucoma; intraocular pressure

Journal Title: Journal of Glaucoma
Year Published: 2020

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