LAUSR

PRCIS Patients with chronic kidney disease are at increased risk for choroidal effusion development following glaucoma surgery. PURPOSE Choroidal effusion is a postoperative complication of glaucoma surgery that results from a transudative fluid collection in the suprachoroidal space. Kidney disease alters bodily fluid dynamics through a variety of mechanisms. The relationship between chronic kidney disease and choroidal effusion following glaucoma surgery has not previously been studied. The purpose of this study was to determine the relationship between chronic kidney disease and choroidal effusion development after glaucoma surgery. PATIENTS AND METHODS This retrospective cohort study consisted of 86 eyes from 86 patients who received glaucoma filtering surgery or transscleral cyclophotocoagulation within the study timeframe. Forty-three patients had chronic kidney disease and 43 patients did not have kidney disease. The main outcome of this study was the development of choroidal effusion measured by Pearson's chi-squared test and multivariate analyses using a binomial regression with a log link. RESULTS Ten patients (23.3%) in the chronic kidney disease group developed choroidal effusion while two patients (4.7%) in the no-kidney disease group developed choroidal effusion (relative risk, 5.0; 95% confidence interval 1.16 to 21.5; P=0.013). The association between chronic kidney disease and choroidal effusion showed mixed results in the multivariate analyses, with some analyses showing a significant association and others showing no significant association. CONCLUSIONS In both the univariate analysis and multivariate analysis, chronic kidney disease was found to be significantly associated with choroidal effusion after glaucoma surgery.