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Supplemental Digital Content is Available in the Text. Targeting intrinsically disordered regions facilitates discovery of T-type/calcium channels 3.2 (CaV3.2) inhibitory peptides. Adeno-associated virus–mediated expression of prototypic CaV3.2iPA1 and 2 in… Click to show full abstract
Supplemental Digital Content is Available in the Text. Targeting intrinsically disordered regions facilitates discovery of T-type/calcium channels 3.2 (CaV3.2) inhibitory peptides. Adeno-associated virus–mediated expression of prototypic CaV3.2iPA1 and 2 in dorsal root ganglia primary sensory neurons in vivo produces sustained inhibition of calcium channel current conducted by CaV3.2/T-type channels and attenuates stimulated and spontaneous pain in rats with neuropathic pain.
Journal Title: Pain
Year Published: 2022
Link to full text (if available)
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