LAUSR

To the Editors: Z olpidem, a member of a family colloquially known as a “Z-drug,” is one of the medications that has been associated with sleepwalking (somnambulism). Aripiprazole is an atypical antipsychotic with dopaminergic partial agonism. So far, only 2 atypical antipsychotics, olanzapine and quetiapine, have been associated with sleepwalking, and the mechanism was related to the serotonergic action. Definite sleepwalking has not been reported in individuals receiving aripiprazole. There is also no evidence suggesting drug-drug interaction between zolpidem and aripiprazole. Here, we present a case of a patient who received zolpidem treatment for several years but developed sleepwalking only after adding aripiprazole during an episode of depression.