LAUSR

Advances in the development of effective combination antiretroviral therapies (ART) have not only extended life expectancy of persons living with HIV (PLWH) but also introduced new health challenges as PLWH encounter older adulthood. As the proportion of PLWH older than 50 years continues to increase, both PLWH and providers may be unprepared to address the resultant complex physical, psychosocial, and biological needs that, in addition toHIV, include geriatric syndromes, chronic multimorbidities, polypharmacy, neurological conditions, and stigma. The needs for research and community resources to address these issues continues to grow. With this context in mind, the “HIV and Aging: From Mitochondria to the Metropolis” conference series (R13AG047064) brings together experts from the fields of gerontology, geriatrics, andHIV every other year to foster collaboration and generate research related to HIV and aging, translate research findings to the community of PLWH, and enhance networking to increase the cadre of multidisciplinary professionals who conduct research related to HIV and aging. The 2019 conference was held in April 2019, in Atlanta, Georgia, USA, and focused on special populations aging with HIV. The aims were to assess the basis for functional wellness in special populations of older PLWH (e.g., women, lesbian, gay, bisexual, transgender, and queer [LGBTQ], persons who use substances) from biological/basic science, social and behavioral, and clinical perspectives and translate information and content into research and clinical care. This article presents a summary of the conference presentations.