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available at http://www.ncbi.nlm.nih.gov/pubmed/31514966 Editorial Comment: Previous series have indicated an association between cardiovascular diseases and erectile dysfunction (ED). This case-control study evaluated the association between prior mitral valve prolapse and ED using data from Taiwan’s National Health Insurance Research Database. A total of 48,755 individuals with ED were identified as cases and 195,020 propensity score matched individuals without ED were selected as controls. Patients with erectile dysfunction had significantly higher odds of previous mitral valve prolapse compared to matched controls. These data continue to support the association between ED and cardiovascular disease. Allen D. Seftel, MD Suggested Reading Burnett AL, Nehra A, Breau RH et al: Erectile dysfunction: AUA guideline. J Urol 2018; 200: 633. Re: Sex, Energy, Well-Being and Low Testosterone: An Exploratory Survey of U.S. Men’s Experiences on Prescription Testosterone A. A. Straftis and P. B. Gray Department of Anthropology, University of Nevada, Las Vegas, Nevada Int J Environ Res Public Health 2019; 16: 3261. doi: 10.3390/ijerph16183261 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/31491933 Editorial Comment: These authors examined patient experiences with prescription testosterone therapy. The study involved an online self-report survey of U.S. patients receiving testosterone who were at least 21 years old. The primary focus was patient perspectives concerning motivations leading to initiation of testosterone therapy and the perceived effects of treatment. The most frequent reasons men gave for taking prescription testosterone were low testosterone (37.1%), well-being (35.2%), energy (28.7%), libido (21.9%) and social energy (19.4%). Older men cited libido as a motivation for testosterone initiation more often than younger men (p <0.001). Men most frequently claimed that testosterone improved energy (52.3%), libido (41.9%) and muscle (28.5%). These are important data to bear in mind as we see many patients with male hypogonadism. Allen D. Seftel, MD Suggested Reading Mulhall JP, Trost LW, Brannigan RE et al: Evaluation and management of testosterone deficiency: AUA guideline. J Urol 2018; 200: 423. 446 MALE AND FEMALE SEXUAL FUNCTION AND DYSFUNCTION; ANDROLOGY Copyright © 2020 American Urological Association Education and Research, Inc. Unauthorized reproduction of this article is prohibited.