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PD10-02 THE MTORC1/2 DUAL INHIBITOR AZD2014 WITH POTENT ANTITUMOR ACTIVITY IN DOCETAXEL SENSITIVE/RESISTANT PROSTATE CANCER IN VITRO

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INTRODUCTION AND OBJECTIVE:The mammalian target of rapamycin (mTOR) is a vital effect factor in regulating cell growth, survival and autophagy via direct interaction with mTORC1 (mTOR complex 1) an... Click to show full abstract

INTRODUCTION AND OBJECTIVE:The mammalian target of rapamycin (mTOR) is a vital effect factor in regulating cell growth, survival and autophagy via direct interaction with mTORC1 (mTOR complex 1) an...

Keywords: pd10 mtorc1; mtorc1 dual; azd2014 potent; potent antitumor; inhibitor azd2014; dual inhibitor

Journal Title: Journal of Urology
Year Published: 2020

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