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Graves’ hyperthyroidism induced pancytopenia, epilepsia and muscle weakness: A case report

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Rationale: Pancytopenia and epilepsia are rare complications of Graves’ disease (GD). Muscle weakness is a physical sign of GD. It is extremely rare for GD patients to present 3 symptoms… Click to show full abstract

Rationale: Pancytopenia and epilepsia are rare complications of Graves’ disease (GD). Muscle weakness is a physical sign of GD. It is extremely rare for GD patients to present 3 symptoms at the same time. Patient concerns: A 35-year-old female was admitted to hospital for dizziness for 1 day. The results of laboratory examination on admission showed pancytopenia and hypothyroidism. Her clinical manifestations include pancytopenia, epilepsy, and muscle weakness. Diagnosis: Graves’ hyperthyroidism. Interventions: She received endotracheal intubation, ventilator, antithyroid drugs, and hormone therapy. Outcome: The patient was discharged after treatment. Lesson: Severe complications caused by GD are rare and require antithyroid therapy. Although glucocorticoid is not recommended by the guidelines, it can effectively improve thrombocytopenia.

Keywords: graves hyperthyroidism; muscle; muscle weakness; pancytopenia epilepsia

Journal Title: Medicine
Year Published: 2022

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