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Updates on hepatitis C virus therapy in the direct-acting antiviral era

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Purpose of review Hepatitis C virus (HCV) is a major cause of clinical burden in the United States and worldwide, as a percentage of patients can develop complications such as… Click to show full abstract

Purpose of review Hepatitis C virus (HCV) is a major cause of clinical burden in the United States and worldwide, as a percentage of patients can develop complications such as cirrhosis and hepatocellular carcinoma. Recent findings Therapy for chronic HCV infection was previously interferon-based, but with the advent of direct-acting antivirals (DAAs), there has been a dramatic improvement in eradicating the virus with favourable side effect profiles. Summary Emerging data are demonstrating new successful agents in difficult-to-manage populations. This review is aimed to provide a brief overview of currently accepted therapy, as well providing new information on upcoming therapeutic agents available for practioners going forward.

Keywords: virus therapy; updates hepatitis; direct acting; hepatitis virus; therapy; virus

Journal Title: Current Opinion in Gastroenterology
Year Published: 2017

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