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On cell death in the intestinal epithelium and its impact on gut homeostasis.

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Purpose of reviewBoth apoptotic and nonapoptotic cell extrusion preserve the barrier functions of epithelia. Live cell extrusion is the paradigm for homeostatic renewal of intestinal epithelial cells (IEC). By extension,… Click to show full abstract

Purpose of reviewBoth apoptotic and nonapoptotic cell extrusion preserve the barrier functions of epithelia. Live cell extrusion is the paradigm for homeostatic renewal of intestinal epithelial cells (IEC). By extension, as extruded cells are not apoptotic, this form of cell shedding is thought to b

Keywords: death intestinal; intestinal epithelium; impact gut; epithelium impact; cell death; cell

Journal Title: Current Opinion in Gastroenterology
Year Published: 2018

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