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Monogenic, polygenic, and oligogenic familial hypercholesterolemia

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Purpose of reviewFamilial hypercholesterolemia has long been considered a monogenic disorder. However, recent advances in genetic analyses have revealed various forms of this disorder, including polygenic and oligogenic familial hypercholesterolemia.… Click to show full abstract

Purpose of reviewFamilial hypercholesterolemia has long been considered a monogenic disorder. However, recent advances in genetic analyses have revealed various forms of this disorder, including polygenic and oligogenic familial hypercholesterolemia. We review the current understanding of the geneti

Keywords: familial hypercholesterolemia; oligogenic familial; hypercholesterolemia; monogenic polygenic; polygenic oligogenic

Journal Title: Current Opinion in Lipidology
Year Published: 2019

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