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Murine Typhus and Hemophagocytic Syndrome.

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had extended to the colon through the mesentery.10,14 It is known that the presence of a retroperitoneal lesion is a definitive risk factor associated with KMP.2 In fact, 4 patients… Click to show full abstract

had extended to the colon through the mesentery.10,14 It is known that the presence of a retroperitoneal lesion is a definitive risk factor associated with KMP.2 In fact, 4 patients in the colon group with a documented retroperitoneal lesion all developed KMP, and 1 died. In contrast, in the small intestine group, only 1 of 5 cases developed KMP and no patient died. We hypothesize that KHE lesions localized to the small intestine are less likely to cause KMP. Although standard therapy for KHE has not been established, surgical treatment was likely to be selected and used successfully in management of KHE lesions in both the small intestine and colon. KHE must be considered in the differential diagnosis of intestinal obstruction in infants and children. Confirmation of retroperitoneal involvement is important in these cases.

Keywords: hemophagocytic syndrome; colon; typhus hemophagocytic; murine typhus; small intestine; khe

Journal Title: Journal of Pediatric Hematology/Oncology
Year Published: 2018

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