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From an evolutionary standpoint, the homologs of human GGCX and PROC are located on the same chromosome only in primates, but not in mice or other species. This relatively new… Click to show full abstract
From an evolutionary standpoint, the homologs of human GGCX and PROC are located on the same chromosome only in primates, but not in mice or other species. This relatively new evolutionary event, which placed 2 mutually counteracting vitamin K-dependent coagulant factors on the same chromosome, forms the basis of both hypocoagulopathy and hypercoagulopathy associated with uniparental disomy of chromosome 2.
Keywords:
splenic infarction;
infarction autosplencetomy;
autosplencetomy first;
massive splenic;
presentation homozygous;
first presentation
Journal Title: Journal of Pediatric Hematology/Oncology
Year Published: 2019
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Journal Title: Journal of Pediatric Hematology/Oncology
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!