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Successful Treatment of Central Nervous System Involvement in Posttransplant EBV-Related Lymphoproliferative Disease With Intrathecal Rituximab Therapy.

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The posttransplant lymphoproliferative disease is a severe cause of morbidity and mortality following allogeneic hematopoietic stem cell transplantation. Central Nervous System involvement in EBV-related PTLD is rare, and there is… Click to show full abstract

The posttransplant lymphoproliferative disease is a severe cause of morbidity and mortality following allogeneic hematopoietic stem cell transplantation. Central Nervous System involvement in EBV-related PTLD is rare, and there is no standard treatment recommendation. We present our patient and discuss other previously reported cases of EBV-associated PTLD with CNS involvement.

Keywords: ebv related; system involvement; central nervous; lymphoproliferative disease; nervous system

Journal Title: Journal of pediatric hematology/oncology
Year Published: 2022

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