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Whole genome sequence of a Treponema pallidum strain from a formalin-fixed paraffin-embedded fine needle aspirate of a cervical lymph node.

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ABSTRACT A patient with unilateral cervical lymphadenopathy suspicious for malignancy underwent a fine needle aspiration. Histology demonstrated mixed inflammatory infiltrates with abundant spirochetes. Sufficient spirochete DNA was extracted from paraffin-embedded… Click to show full abstract

ABSTRACT A patient with unilateral cervical lymphadenopathy suspicious for malignancy underwent a fine needle aspiration. Histology demonstrated mixed inflammatory infiltrates with abundant spirochetes. Sufficient spirochete DNA was extracted from paraffin-embedded tissue sections to obtain the near-complete genome sequence of a macrolide resistant strain belonging to the SS14 omega strain of Treponema pallidum.

Keywords: fine needle; treponema pallidum; genome sequence; paraffin embedded

Journal Title: Sexually transmitted diseases
Year Published: 2023

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