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The ISGyP Endocervical Adenocarcinoma Project

It is with great enthusiasm that I am addressing all of you to introduce this special issue of the International Journal of Gynecologic Pathology dedicated in its entirety to the… Click to show full abstract

It is with great enthusiasm that I am addressing all of you to introduce this special issue of the International Journal of Gynecologic Pathology dedicated in its entirety to the ISGyP Endocervical Adenocarcinoma Project. I would like to thank most deeply the “Endocervical Adenocarcinoma Group” for the tremendous efforts of each of the members in the undertaking and completion of this endeavor which has resulted in nine individual articles related to endocervical adenocarcinoma (highlighted below). I also want to thank all the members of the Society for their participation and support in this project. They helped to provide a set of consensus recommendations relating to many problematic aspects of endocervical adenocarcinoma as a society, recommendations of best-practice guidelines for our daily work. I also want to thank Dr Elvio Silva for his advice and support. The ISGyP endocervical adenocarcinoma project was launched in the middle of 2019 to build evidence-based and/or best-practice recommendations for pathologic reporting of all aspects of cervical adenocarcinoma and had 3 main aims: (1) to understand the spectrum of current practices in pathologic evaluation (management, gross, diagnosis, and classification) and reporting of endocervical adenocarcinoma with a review of the literature including controversial areas as well as a member survey; (2) to improve global reproducibility of endocervical adenocarcinoma classification and pathologic reporting; and (3) to assess prognostic significance of WHO/IECC endocervical adenocarcinoma classification and Silva pattern-based classification of human papillomavirus (HPV)-associated adenocarcinomas. A dedicated meeting was held on February 29, 2020, in advance of the annual ISGyP Symposium and USCAP meetings held in Los Angeles (Fig. 1). The articles that constitute this special issue of the International Journal of Gynecologic Pathology include a survey of current individual practices, results of online training and self-assessment in the histopathologic classification of endocervical adenocarcinoma and diagnosis of patterns of invasion, and evidence-based and/or practice-based recommendations on gross examination and processing, including intraoperative evaluation, distinction of in situ from invasive adenocarcinoma and Silva patterns of invasion; grading of endocervical adenocarcinoma; tumor typing including immunohistochemistry; staging of endocervical adenocarcinoma; and predictive markers. A brief report on participation includes results of voting on the recommendations that have been put forward. As the first step of this vast endocervical project, an exhaustive survey was designed to gather information on existing practices regarding grossing, processing, diagnosing and reporting of cervical adenocarcinoma among the members of the society. The survey was completed by 175 members of the society around the world (page S4). A key task of our society is to be part of the decision strategies. The work of our society can have a tremendous impact in changing practices in our field and in those of our colleagues. Thus, the ISGyP Endocervical Adenocarcinoma Data Collection Project was created with ISGyP members from 112 centers from around the globe offering to participate in contributing anonymized patient data to assess the From the Pathology Department, Massachusetts General Hospital, Boston, MA. The author declares no conflict of interest. Address correspondence to Esther Oliva, MD, Pathology Department, Massachusetts General Hospital, 55 Fruit St., Boston, MA 02114. E-mail: [email protected]. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Keywords: adenocarcinoma; pathology; isgyp endocervical; adenocarcinoma project; endocervical adenocarcinoma

Journal Title: International Journal of Gynecological Pathology
Year Published: 2021

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